Pure Encapsulations · Alpha-GPC · Capsules

Is Pure Encapsulations Alpha-GPC underdosed?

1 serving = 2 capsulesDirections: 3 servings a dayLabel as of 25 Mar 2021 · NIH DSLD

Verdict

1.2 g a dayas the label directs · studies use 250–600 mg/day of alpha-gpc

Effective dose

Taken as the label directs (3 servings a day, 400 mg each), it gives 1.2 g a day; studies use 250–600 mg/day. The most the directions give is above the range studies use.

One capsule gives 200 mg, so reaching the low end of what studies use (250 mg) takes 1.3 capsules a day; it ranks 4th of 9 alpha-GPC supplements here by dose.

2 capsules a day reach 250 mg.

What the label says

Alpha-GPC per serving
400 mg in 2 capsules
Servings a day
3 servings a day
Alpha-GPC a day, as directed
1.2 g
Research dose
250–600 mg/day Evidence: Weak
Recommendations: As a dietary supplement, take 2 caplique capsules, 3 times daily, with or between meals.
The label's directions, as printed.

More about alpha-gpc: forms, timing and the studies behind the dose.

Same category, compared

All 9 alpha-GPC supplements we checked, ranked by dose (commission never changes the order). Studies use 250–600 mg/day of alpha-gpc; servings counted to 250 mg.

ProductPer servingServings to reach itForm
Double Wood Alpha-GPC 300 mg600 mg1 or lessCapsules
NOW Alpha GPC 300 mg600 mg1 or lessCapsules
Nutricost Alpha GPC 600 mg600 mg1 or lessCapsules
Pure Encapsulations Alpha-GPC (this product)400 mg1 or lessCapsules
BulkSupplements Alpha GPC 300 mg Capsules300 mg1 or lessCapsules
Jarrow Formulas Alpha GPC 300 mg300 mg1 or lessCapsules
NutraBio Alpha GPC300 mg1 or lessCapsules
Swanson Alpha-GPC 300 mg300 mg1 or lessCapsules
Nootropics Depot Alpha GPC 150 mg Capsules150 mg1.7Capsules

Where the reference doses come from

  1. Alpha-GPC, 250–600 mg/day: Bellar et al., 2015; Marcus et al., 2017.
  2. Label data: National Institutes of Health, Office of Dietary Supplements. Dietary Supplement Label Database, 2026. https://dsld.od.nih.gov/. Label 245969, including its servings a day.

For a supplement taken every day we judge the most the label's directions give in a day, and show the least. Read the full methodology or the corrections log.