Is PEScience Prolific underdosed?

• L-CitrullinePer scoop 3 gStudies 4–5.33 gEffective doseEvidence: Weak

  Contains 6 g; studies use 4–5.33 g.

• Betaine AnhydrousPer scoop 1.25 gStudies 2.5 g/dayEffective doseEvidence: Moderate

  Contains 2.5 g; studies use 2.5 g/day.

• TaurinePer scoop 750 mgStudies 1–6 gEffective doseEvidence: Moderate

  Contains 1.5 g; studies use 1–6 g.

• CaffeineLabel: Caffeine (Caffeine Anhydrous, Infinergy)Per scoop 160 mgStudies 3–6 mg/kgEffective doseEvidence: Strong

  Contains 320 mg (4.3 mg/kg at 75 kg); studies use 3–6 mg/kg.

• L-TheaninePer scoop 100 mgStudies 100–200 mgEffective doseEvidence: Weak

  Contains 200 mg; studies use 100–200 mg.

• Cognizin (Citicoline)Per scoop 50 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: we have no research dose for it from exercise studies.

• Rhodiola rosea Root ExtractPer scoop 50 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: we have no research dose for it from exercise studies.

• NeuroFactor (Coffee Fruit Extract)Per scoop 50 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: we have no research dose for it from exercise studies.

Use “Check it for your dose” to see this table for your own scoops and bodyweight. Only caffeine is dosed per kilogram in the studies we cite; the other research doses are fixed amounts, so your weight doesn't change them.

How many scoops would it take?

To reach the low end of the research dose for each underdosed ingredient.

Taking more doesn't fix this product. Reaching those doses means more than 400 mg of caffeine from the scoops alone, above the FDA's 400 mg daily reference for most adults, before any coffee.

Where the reference doses come from

1. Betaine Anhydrous, 2.5 g/day: Cholewa et al., 2013Hoffman et al., 2009Zawieja et al., 2024.
2. Caffeine, 3–6 mg/kg: Guest et al., 2021.
3. L-Citrulline, 4–5.33 g: Gough et al., 2021Vårvik et al., 2021.
4. L-Theanine, 100–200 mg: Owen et al., 2008Payne et al., 2025.
5. Taurine, 1–6 g: Deng et al., 2025Waldron et al., 2018.
6. Daily caffeine reference, 400 mg: US FDA, Spilling the Beans.
7. Label data: National Institutes of Health, Office of Dietary Supplements. Dietary Supplement Label Database, 2026. https://dsld.od.nih.gov/. Label 318596.

Methodology 1.11. Read the full methodology or the corrections log.