Is NutraBio PRE underdosed?

• Vitamin CLabel: Vitamin C (Ascorbic Acid) [USP]Per scoop 150 mgStudies Not setNot gradedEvidence: Not graded

  Contains 150 mg. A vitamin or mineral: we grade a pre-workout’s ingredients against exercise studies; vitamins and minerals are graded only on their own supplement pages.

• Niacin (Vitamin B3)Per scoop 30 mg NE, as printedStudies Not setNot gradedEvidence: Not graded

  Not graded: a vitamin or mineral. We grade a pre-workout’s ingredients against exercise studies; vitamins and minerals are graded only on their own supplement pages.

• Vitamin B6 (Pyridoxine Hydrochloride)Per scoop 50 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: a vitamin or mineral. We grade a pre-workout’s ingredients against exercise studies; vitamins and minerals are graded only on their own supplement pages.

• Vitamin B12 (Methylcobalamin)Per scoop 150 mcgStudies Not setNot gradedEvidence: Not graded

  Not graded: a vitamin or mineral. We grade a pre-workout’s ingredients against exercise studies; vitamins and minerals are graded only on their own supplement pages.

• Calcium (Calci-K)Per scoop 95 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: a vitamin or mineral. We grade a pre-workout’s ingredients against exercise studies; vitamins and minerals are graded only on their own supplement pages.

• Phosphorus (Calci-K, Sodium Phosphate)Per scoop 89 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: a vitamin or mineral. We grade a pre-workout’s ingredients against exercise studies; vitamins and minerals are graded only on their own supplement pages.

• Magnesium (Magnesium Creatine Chelate)Per scoop 40 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: a vitamin or mineral. We grade a pre-workout’s ingredients against exercise studies; vitamins and minerals are graded only on their own supplement pages.

• Sodium (Sodium Phosphate)Per scoop 60 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: a vitamin or mineral. We grade a pre-workout’s ingredients against exercise studies; vitamins and minerals are graded only on their own supplement pages.

• Potassium (Calci-K)Per scoop 80 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: a vitamin or mineral. We grade a pre-workout’s ingredients against exercise studies; vitamins and minerals are graded only on their own supplement pages.

• CholineLabel: Choline (Choline Bitartrate)Per scoop 205 mgStudies Not setNot gradedEvidence: Not graded

  Contains 205 mg. Not graded: most people get enough choline from food, and a review of the exercise studies found supplements might only help endurance when very long, hard exercise lowers blood choline (Penry and Manore, 2008).

• L-LeucineLabel: L-Leucine [fermented]Per scoop 3.5 gStudies 2–3 gEffective doseEvidence: Moderate

  Contains 3.5 g; studies use 2–3 g.

• Beta-AlaninePer scoop 3.2 gStudies 3.2–6.4 g/dayEffective doseEvidence: Strong

  Contains 3.2 g; studies use 3.2–6.4 g/day.

• Creatine MonohydrateLabel: PharmaPure (Creatine Monohydrate)Per scoop 3 gStudies 3–5 g/dayEffective doseEvidence: Strong

  Contains 3 g; studies use 3–5 g/day.

• Betaine AnhydrousLabel: Betaine Anhydrous (Trimethylglycine)Per scoop 2.5 gStudies 2.5 g/dayEffective doseEvidence: Moderate

  Contains 2.5 g; studies use 2.5 g/day.

• Creatine MagnaPower (Magnesium Creatine Chelate)Per scoop 500 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: the label gives it in a form or blend we can't turn into a dose (no stated ratio or amount), so it isn't counted. See the methodology.

• L-CitrullineLabel: L-Citrulline [fermented]Per scoop 6 gStudies 4–5.33 gEffective doseEvidence: Weak

  Contains 6 g; studies use 4–5.33 g.

• Agmatine SulfatePer scoop 1 gStudies Not setNot gradedEvidence: Not graded

  Contains 1 g. Not graded: no human study has tested it for exercise; human studies are for nerve pain.

• Arginine Silicate (Nitrosigine)Label: Nitrosigine (Inositol-Stabilized Arginine Silicate)Per scoop 750 mgStudies 1.5 gBelow research doseEvidence: Weak

  Contains 750 mg; studies use 1.5 g.

• L-TyrosinePer scoop 1.5 gStudies Not setNot gradedEvidence: Not graded

  Contains 1.5 g. Not graded: a 2023 meta-analysis found no effect on endurance; its evidence is for focus under stress, at about 150 mg per kg of bodyweight.

• Choline BitartratePer scoop 500 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: we have no research dose for it from exercise studies.

• CaffeineLabel: Caffeine Anhydrous [USP]; CaffeinePer scoop 350 mgStudies 3–6 mg/kgEffective doseEvidence: Strong

  Contains 350 mg (4.7 mg/kg at 75 kg); studies use 3–6 mg/kg.

• L-TheanineLabel: TheaPure L-Theanine (L-Theanine)Per scoop 300 mgStudies 100–200 mgEffective doseEvidence: Weak

  Contains 300 mg; studies use 100–200 mg.

• Huperzia serrata Leaf Extract [standardized extract]Per scoop 10 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: we have no research dose for it from exercise studies.

• TaurinePer scoop 2 gStudies 1–6 gEffective doseEvidence: Moderate

  Contains 2 g; studies use 1–6 g.

• Calci-K (Calcium Potassium Phosphate Citrate)Per scoop 525 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: we have no research dose for it from exercise studies.

• Sodium PhosphatePer scoop 189 mgStudies Not setNot gradedEvidence: Not graded

  Not graded: a vitamin or mineral. We grade a pre-workout’s ingredients against exercise studies; vitamins and minerals are graded only on their own supplement pages.

Use “Check it for your dose” to see this table for your own scoops and bodyweight. Only caffeine is dosed per kilogram in the studies we cite; the other research doses are fixed amounts, so your weight doesn't change them.

How many scoops would it take?

To reach the low end of the research dose for each underdosed ingredient.

Taking more doesn't fix this product. Reaching those doses means more than 400 mg of caffeine from the scoops alone, above the FDA's 400 mg daily reference for most adults, before any coffee.

Where the reference doses come from

1. Arginine Silicate (Nitrosigine), 1.5 g: Kalman et al., 2016Rogers et al., 2020.
2. Beta-Alanine, 3.2–6.4 g/day: Harris et al., 2006Hobson et al., 2012Trexler et al., 2015.
3. Betaine Anhydrous, 2.5 g/day: Cholewa et al., 2013Hoffman et al., 2009Zawieja et al., 2024.
4. Caffeine, 3–6 mg/kg: Guest et al., 2021.
5. Creatine Monohydrate, 3–5 g/day: Kreider et al., 2017.
6. L-Citrulline, 4–5.33 g: Gough et al., 2021Vårvik et al., 2021.
7. L-Leucine, 2–3 g: Jäger et al., 2017Kerksick et al., 2018.
8. L-Theanine, 100–200 mg: Owen et al., 2008Payne et al., 2025.
9. Taurine, 1–6 g: Deng et al., 2025Waldron et al., 2018.
10. Vitamin C, 200–1000 mg/day: Frei et al., 2012Gonzalez et al., 2026Levine et al., 1996.
11. Daily caffeine reference, 400 mg: US FDA, Spilling the Beans.
12. Label data: National Institutes of Health, Office of Dietary Supplements. Dietary Supplement Label Database, 2026. https://dsld.od.nih.gov/. Label 333482.

Methodology 1.11. Read the full methodology or the corrections log.