Ingredient
L-Arginine
Research dose
0.15 g/kg
Evidence: Weak Taken before training: what counts is the amount in the serving you take. The amount scales with bodyweight; product pages use 75 kg unless you change it.
A meta-analysis suggests 0.15 g per kg of bodyweight 60–90 minutes before exercise; a published comment (Trexler, 2025) found errors that inflate its results, and the ISSN review says most arginine studies found no benefit.
Sources
Viribay A, Burgos J, Fernández-Landa J, Seco-Calvo J, Mielgo-Ayuso J. Effects of Arginine Supplementation on Athletic Performance Based on Energy Metabolism: A Systematic Review and Meta-Analysis. Nutrients. 2020;12(5):1300.
Supports the research dose. Where: Abstract: "should be adjusted to 0.15 g/kg of body weight ingested between 60-90 min before". Read the source, checked 7 Oct 2026.
L-arginine supplements we've checked
17 L-arginine supplements, each judged on how much a day its label's own directions give. See them all, ranked.
In the pre-workouts we've checked
| Product | Per scoop | Verdict |
|---|---|---|
| PEScience High Volume | 734 mg | Below research dose |
| Cellucor C4 Ultimate Shred | 3 g | Below research dose |
| Cellucor C4 Ultimate | 3 g | Below research dose |
| Apollon Nutrition Bare Knuckle | 551 mg | Below research dose |
| Cellucor C4 Original | 1.2 g | Below research dose |
| Cellucor C4 Sport | In a blend | Hidden in a blend |
| Ghost Pump | 1.1 g | Below research dose |
| Naked Nutrition Naked Energy | 500 mg | Below research dose |
| RSP Nutrition AminoLean | In a blend | Hidden in a blend |